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Apigenin acts as a monoamine transporter activator, one of the few chemicals demonstrated to possess this property. [8] Apigenin is a weak ligand for central benzodiazepine receptors in vitro and exerts anxiolytic and slight sedative effects in an animal model . [9] Apigenin shows second-order positive modulatory activity at GABA A receptors. [10] [11] It has also effects on adenosine receptors [12] and is an acute antagonist at the NMDA receptors ( IC 50 = 10 μM). [11] In addition, like various other flavonoids, apigenin has been found to possess nanomolar affinity for the opioid receptors (K e = 410 nM, 970 nM, and 410 nM for the μ- , δ- , and κ-opioid receptors , respectively), acting as a non-selective antagonist of all three opioid receptors. [13]

Trenbolone hexabol

trenbolone hexabol

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