As previously noted, cholesterol levels can change when oral steroids are used, even for short periods. Recent research has pointed the finger at cholesterol as being one of the most important steroid related side effects bodybuilders want to avoid. The thickening of the blood (red blood count RBC), artery plaque, high blood pressure, high LDL and low HDL can and will lead to coronary heart disease (CHD) if adequate precautions aren’t taken. It is thus advised; all oral steroids are taken for cycles of 6-8 weeks and no longer. Support supplements are also advised, these include: Curcumin, Citrus Bergamot, Vitamin K2, Omega-3.
Of concern to any user of Winstrol during a cycle should be its intoxicating effect on the liver . The drug is a 17aa structured steroid , meaning it has been structured in a way which allows it to be orally bio-available, yet this has the negative effect of making Winstrol potentially harmful to the liver. It is therefore paramount the duration of a Winstrol cycle is limited, the dose of the drug is not excessive, the user does not stack it with other hepatotoxic compounds, does not drink alcohol whilst on cycle, and does not use Winstrol if they have an underlying medical condition which effects the livers health. There are supplements available which also help protect the liver (Milk Thistle, Liv-52 etc), and these would be advisable during any Winstrol cycle .
Transdermal patches (adhesive patches placed on the skin) may also be used to deliver a steady dose through the skin and into the bloodstream. Testosterone-containing creams and gels that are applied daily to the skin are also available, but absorption is inefficient (roughly 10%, varying between individuals) and these treatments tend to be more expensive. Individuals who are especially physically active and/or bathe often may not be good candidates, since the medication can be washed off and may take up to six hours to be fully absorbed. There is also the risk that an intimate partner or child may come in contact with the application site and inadvertently dose himself or herself; children and women are highly sensitive to testosterone and can suffer unintended masculinization and health effects, even from small doses. Injection is the most common method used by individuals administering AAS for non-medical purposes.